Figure 4.

Comparison of expression profiles generated by Illumina_Human_WG_v2 and spotted oligonucleotide microarrays. A) Coriell-18 samples were analyzed in parallel on two different types of microarrays: Illumina_Human_WG_v2 ("Illumina") and spotted oligonucleotide microarrays manufactured in the NHGRI core facility ("NHGRI"). Genes were ranked according to nominal P values of the t tests, and top ~5% of genes in each list were chosen for the intersection analysis; B) Bar plot represents fold difference of expression values (NF1-affecteds vs. NF1-unaffecteds) for the overlapping genes. Each overlapping transcript is represented by a pair of bars. Blue bars denote transcripts on Illumina platform; orange bars denote transcripts on the NHGRI platform. Numbers on X-axis represent transcripts in the overlap (114 total).