Open Access Research article

Use of microarray technology to assess the time course of liver stress response after confinement exposure in gilthead sea bream (Sparus aurata L.)

Josep A Calduch-Giner1, Grace Davey2, Alfonso Saera-Vila1, Benoit Houeix2, Anita Talbot2, Patrick Prunet3, Michael T Cairns2 and Jaume Pérez-Sánchez1*

Author Affiliations

1 Fish Nutrition and Growth Endocrinology Group, Department of Biology, Culture and Pathology of Marine Fish Species, Institute of Aquaculture Torre de la Sal (CSIC), 12595 Ribera de Cabanes, Castellón, Spain

2 Martin Ryan Institute, National University of Ireland, Galway, Ireland

3 INRA-SCRIBE, Fish Adaptation and Stress Group, IFR Reproduction, Development and Ecophysiology, Rennes Cedex, France

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BMC Genomics 2010, 11:193  doi:10.1186/1471-2164-11-193

Published: 22 March 2010

Additional files

Additional file 1:

K-means clustering of up-regulated genes (Sets 1, 2, 3). Genes involved in similar pathways or processes are grouped and with the same font (italic/non-italic).

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Additional file 2:

Plasma cortisol levels of control (open circles) and stressed (filled circles) fish. Data are the mean ± SEM (n = 5). Different letters indicate statistically significant changes over the course of the experiment in stressed fish (ANOVA, P < 0.05). Statistically significant differences between stressed and control fish were analyzed at each sampling time by means of Student t-test (*P < 0.05, **P < 0.01, ***P < 0.001).

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