Tachystatin-type and linear AMPs. A. Multiple sequence alignment of tachystatin-type AMPs. A red arrow represents a phase 0 intron; B. Model structure of naickin-1 and its superimposition with tachystatin-B1; C. Nahelixin. Signal peptide and mature peptides are shaded in gray and yellow, respectively. In the alignment of nahelixin with known AMPs from frog, identical residues are bolded and shadowed in yellow while conservative substitutions are in gray. Structure modeled ab initio is displayed in ribbon with hydrophobic residues in pink and hydrophilic residues in blue. The helical wheel projection shows the amphiphilic characteristics of nahelixin. Putative proprotein cleavage sites are boxed in black. Tt: Tachypleus tridentatus, Pc: Psalmopoeus cambridgei, Al: Acrocinus longimanus, Bh: Bradysia hygida, Mc: Mesembryanthemum crystallinum, Mj: Mirabilis jalapa, Pa: Phytolacca americana, Ppa: Pseudis paradoxa.
Tian et al. BMC Genomics 2010 11:187 doi:10.1186/1471-2164-11-187