A proposed exon shuffling mechanism for origin of nabaecin. A. Sequence alignment of abaecin, nabaecin-3 and navitripenicin. Identical nucleotides and amino acids are shadowed in yellow and signal peptides are italized and underlined once. Alignable sequences are bolded and the corresponding nucleotides are boxed. Intron splice sites are showed in gray and omitted sequences are displayed as dots. Stop codons are shadowed in dark gray; B. The exon-shuffing model (for detailed description, see the text). Color codes are the same with those in Figure 12A.
Tian et al. BMC Genomics 2010 11:187 doi:10.1186/1471-2164-11-187