Table 3

Overlapping gene pairs on opposing strands

Group

N

Co-expressiona

mRNA abundanceb

P (compared to random pairs)c


1

3' overlap

948

-0.019

8.39

0.0020

2

5' overlap

23

0.140

7.99

0.142

3

fully containedd

17

-0.084

7.30

0.103


aAverage Pearson correlation coefficient

b average mRNA abundance for all genes is 7.73 (log2 signal intensity).

c To derive a Null expectation, we analyzed 100,000 pairs of randomly chosen genes; mean Pearson correlation of this random dataset is 0.014. P-values from Wilcoxon rank sum tests.

d the shorter gene is fully contained in the longer gene (but transcribed from the opposite DNA strand)

Chen et al. BMC Genomics 2010 11:178   doi:10.1186/1471-2164-11-178

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