Table 4 |
|
|
The ten most coherent TFBS-cluster gene signatures according to the Ingenuity softwarea |
|
|
p-value |
|
|
|
|
|
GC, ETF, AP2GAMMA, MOVB, AP2, LRF, CHCH, SP1, AP2LAPHA |
|
|
Cellular Development (MCF) |
4.32E-13 |
|
Organ Development (PSDF) |
2.43E-14 |
|
Wnt/b-catenin Signaling(CP) |
3.90E-10 |
|
CKROX, SPZ1, WT1, MZF1, MAZ, TFIII, IK |
|
|
Cellular Development (MCF) |
3.97E-12 |
|
Tissue Development (PSDF) |
1.23E-12 |
|
Wnt/b-catenin Signaling (CF) |
1.51E-05 |
|
AML, COREBINDINGFACTOR, PEBP, OSF2, AML1 |
|
|
Cell-To-Cell Signaling and Interaction (MCF) |
5.29E-05 |
|
Hematological System Development and Function (PSDF) |
3.08E-05 |
|
Immune Cell Trafficking (PSDF) |
3.08E-05 |
|
CACBINDINGPROTEIN, CACD, PAX4, SREBP1 |
|
|
Cellular Development (MCF) |
6.48E-12 |
|
Organismal Development (PSDF) |
4.92E-16 |
|
Axonal Guidance Signaling (CP) |
4.26E-05 |
|
HMGIY, STAT6, STAT1, NFAT |
|
|
Cellular Development (MCF) |
2.43E-08 |
|
Nervous System Development and Function (PSDF) |
6.45E-18 |
|
Axonal Guidance Signaling (CF) |
4.24E-04 |
|
CEBPDELTA, CEBPB, CEBPA |
|
|
Antigen Presentation (MCF) |
4.28E-04 |
|
Humoral Immune Response (PSDF) |
2.98E-04 |
|
T Helper Cell Differentiation (CP) |
1.61E-03 |
|
ZF5, E2F, KROX |
|
|
Gene Expression (MCF) |
6.32E-22 |
|
Organ Development (PSDF) |
5.59E-16 |
|
Axonal Guidance Signaling (CP) |
1.13E-12 |
|
ZTA, BACH2, BACH1 |
|
|
Antigen Presentation (MCF) |
1.35E-06 |
|
Cell-mediated Immune Response (PSDF) |
1.35E-06 |
|
NF-kB Signaling (CP) |
1.71E-03 |
|
CREL, NFKAPPAB65 |
|
|
Cell-To-Cell Signaling and Interaction (MCF) |
2.73E-05 |
|
Cell-mediated Immune Response (PSDF) |
1.81E-06 |
|
NF-kB Signaling (CP) |
4.28E-06 |
|
MAZR, ZNF219 |
|
|
Cellular Development (MCF) |
9.61E-13 |
|
Nervous System Development and Function (PSDF) |
1.23E-10 |
|
Axonal Guidance Signaling (CP) |
1.40E-07 |
|
|
|
|
a Only the top categories with respect to p-value are given |
|
|
Veerla et al. BMC Genomics 2010 11:145 doi:10.1186/1471-2164-11-145 |
|
