Intra and inter-run variation in UHRR samples: Nested-ANOVA. The results of a nested-ANOVA, quantifying the probe-wise components of variation corresponding to the within (blue) and between (green) batch variance. The model and calculation used are as described in methods. Effects on these standard deviations after detection-filtering (DF), quantile-normalisation (QN), mean-centring (MC), and ComBat (CB) are shown.
Kitchen et al. BMC Genomics 2010 11:134 doi:10.1186/1471-2164-11-134