Table 2

Top 20 Annotated Transcripts Downregulated in Light-induced Plasmodia

Contig ID

SwissProt

Annotation

hits(D)

hits(L)

relD/relL

P-value


contig10338_1

P36618

Cell division control protein 16, CDC16

40

1

31.7301

7.48E-10


contig10470_1

P20072

Annexin A7

68

2

26.9706

1.54E-15


contig00397_1

Q5BMR2

Phospholipase D (PLD1)

62

2

24.5908

4.31E-14


contig00525_1

Q7EYV7

Poly ADP-ribose polymerase 1 (PARP-1)

244

10

19.3554

5.19E-49


contig11321_1

P38750

Uncharacterized transporter YHL008C

24

1

19.0381

5.43E-06


contig00901_1

P16064

Subtilisin inhibitor 1, ASI-I

21

1

16.6583

2.79E-05


PpolyN1a03a12

Q07346

Glutamate decarboxylase, GAD

20

1

15.8651

4.80E-05


PpolyN1a02c07

P34121

Coactosin, coaA

56

3

14.8074

1.07E-11


contig11574_1

P39749

Flap endonuclease 1, FEN-1

18

1

14.2786

0.000141


contig10414_1

Q5UNX2

Putative ankyrin repeat protein, YL715

90

5

14.2786

8.82E-18


contig03548_1

O49286

F-box/LRR-repeat protein 5, FBL5

17

1

13.4853

0.000242


contig00369_1

Q80U58

Pumilio homolog 2

17

1

13.4853

0.000242


contig10457_1

Q8WN03

Kv channel-interacting protein 2, Kcnip2

16

1

12.6921

0.000412


contig00264_1

P13466

Actin-binding protein 120, ABP-120

32

2

12.6921

5.26E-07


contig02333_1

Q8RWN7

POLTERGEIST Protein phosphatase 2C 32, PP2C

15

1

11.8988

0.000701


contig01650_1

O24496

Glyoxalase II, Glx II

15

1

11.8988

0.000701


contig01322_1

Q94B74

NADH pyrophosphatase

15

1

11.8988

0.000701


contig08310_1

Q10MW3

Pyruvate decarboxylase isozyme 2, PDC2

73

5

11.5815

6.84E-14


contig00558_1

P18281

Actobindin

29

2

11.5022

2.55E-06


contig11873_1

O10296

Apoptosis inhibitor 1, IAP-1

28

2

11.1055

4.30E-06


Transcripts with unambiguous annotations, significant differential expression (P < 0.05), and that possess the highest levels of downregulation (relD/relL > 1.0), are listed. BLAST2GO [15] automatic annotations were used, and manual corrections of annotations were included in some cases.

Barrantes et al. BMC Genomics 2010 11:115   doi:10.1186/1471-2164-11-115

Open Data