Figure 3.

Methanol metabolism. Overview of the methanol metabolism in H. polymorpha. The fold upregulation of the indicated genes is shown in red. GAP: glyceraldehyde-3-phosphate; DHA: dihydroxyacetone; DHAP: dihydroxyacetone phosphate; FBP: fructose bisphosphate; F6P: fructose-6-phosphate; XU5P: xylulose-5-phosphate; GSH: reduced glutathione; GS-CH₂OH: S-hydroxymethylglutathione; GS-CHO: S-formylglutathione. AOX: alcohol oxidase; CAT: catalase; DHAS: dihydroxyacetone synthase; DAK: dihydroxyacetone kinase; FLD: formaldehyde dehydrogenase; FGH: S-formyl glutathione hydrolase and FMD: formate dehydrogenase.