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Open Access Research article

Sequence determinants of human microsatellite variability

Trevor J Pemberton1*, Conner I Sandefur2, Mattias Jakobsson13 and Noah A Rosenberg12

Author Affiliations

1 Department of Human Genetics, University of Michigan, 100 Washtenaw Avenue, Ann Arbor, Michigan 48109 USA

2 Center for Computational Medicine and Biology, University of Michigan, 100 Washtenaw Avenue, Ann Arbor, Michigan 48109 USA

3 Department of Evolutionary Biology, Evolutionary Biology Center, Uppsala University, Norbyvägen 18D, SE-752 36 Uppsala, Sweden

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BMC Genomics 2009, 10:612  doi:10.1186/1471-2164-10-612

Published: 16 December 2009

Additional files

Additional file 1:

Table S1. The primer sequences, extracted human RefSeq sequence, and the repeat structure identified within that sequence (demarcated by square brackets in the RefSeq sequence), for each of the 627 microsatellite loci used in the population-genetic analysis.

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Additional file 2:

Table S2. The variables calculated for each of the 627 microsatellite loci used in the population-genetic analysis.

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Additional file 3:

Table S3. The effect of chromosome number on the different sequence properties and measures of variation across individuals.

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Additional file 4:

Table S4. Summary of the properties of measures of variation across individuals.

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Additional file 5:

Table S5. Spearman's rank correlations between measures of variation across individuals for microsatellites with one or two separate STR regions embedded in their sequence.

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Additional file 6:

Table S6. Spearman's rank correlations between measures of variation across individuals for microsatellites with three separate tetra-nucleotide STR regions embedded in their sequence.

Format: PDF Size: 79KB Download file

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