Open Access Research article

A new deep branch of eurasian mtDNA macrohaplogroup M reveals additional complexity regarding the settlement of Madagascar

François-X Ricaut12*, Harilanto Razafindrazaka1, Murray P Cox3, Jean-M Dugoujon1, Evelyne Guitard1, Clement Sambo4, Maru Mormina5, Marta Mirazon-Lahr5, Bertrand Ludes16 and Eric Crubézy1

Author Affiliations

1 CNRS FRE 2960, Laboratoire d'Anthropobiologie, Université de Toulouse, Toulouse III Paul sabatier, 37 allées Jules Guesde, 31073 Toulouse cedex 3, France

2 Center for Archaeological Sciences, Katholieke Universiteit Leuven, Celestijnenlaan 200E, 3001 Heverlee, Belgium

3 Institute of Molecular BioSciences, Allan Wilson Centre for Molecular Ecology and Evolution, and the Bio-Protection Centre, Massey University, Palmerston North 4442, New Zealand

4 Ecole Normale Supérieure, Université de Toliara, Toliara, Madagascar

5 Leverhulme Centre for Human Evolutionary Studies, Henry Wellcome Building, Fitzwilliam Street, University of Cambridge, Cambridge CB2 1QH, UK

6 Laboratoire d'Anthropologie Moléculaire, Institut de Médecine Légale, 11 rue Humann, 67085 Strasbourg, France

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BMC Genomics 2009, 10:605  doi:10.1186/1471-2164-10-605

Published: 14 December 2009

Additional files

Additional file 1:

Distribution of diagnostic mtDNA control region polymorphisms in haplogroup M23 (73G 152C 195C 204C 263G 315.1C 417A 489C 533G 16223T 16263C 16311C 16519C) from available databases. The table displays the occurrence of the mtDNA control region diagnostic polymorphisms of haplogroup M23 in six mtDNA databases (≤1 mismatch).

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Additional file 2:

Distribution of HVS1 polymorphisms defining haplogroup M23 within sub-Saharan African populations. The table displays the occurrence of the M23 HVS1 motif in 7,262 sub-Saharan Africans.

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Additional file 3:

Reference list for the supplemental citations in Additional files1and2.

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