Table 1

Under-represented toxin encoding transcripts from the Echis vgDbESTs potentially associated with venom function.

Identification

No. of ESTs

Species present

Activty

Possible venom function

Aminopeptidase

8

E. c. sochureki

Hydrolysis of the N-terminal region of peptides [82].

Potential interference with angiogenesis and blood pressure control [83,84].

1

E. coloratus

Ectonucletotide pyrophosphatase/phosphodiesterase

2

E. coloratus

Hydrolysis of nucleotides and nucleic acids [85].

Interaction with platelet function [85]. Activity previously described in Echis carinatus [86].

3

E. c. sochureki

5'-nucleotidase

3

E. coloratus

Cleavage of a wide variety of ribose and deoxyribose nucleotides [1].

Potential inhibitor of platelet aggregation [1]. Activity identified in a number of different lineages including Echis carinatus [86].

2

E. p. leakeyi

1

E. c. sochureki

Ectonucleoside triphosphate diphosphohydrolase 2 (E-NTPase 2)

2

E. coloratus

Hydrolysis of nucleoside-5'-triphosphates and diphosphates [87].

Potential inhibitor of platelet aggregation [87,88].

Casewell et al. BMC Genomics 2009 10:564   doi:10.1186/1471-2164-10-564