Open Access Highly Accessed Open Badges Research article

Evidence for niche adaptation in the genome of the bovine pathogen Streptococcus uberis

Philip N Ward1, Matthew TG Holden2*, James A Leigh3, Nicola Lennard2, Alexandra Bignell2, Andy Barron2, Louise Clark2, Michael A Quail2, John Woodward2, Bart G Barrell2, Sharon A Egan3, Terence R Field4, Duncan Maskell5, Michael Kehoe6, Christopher G Dowson7, Neil Chanter8, Adrian M Whatmore79, Stephen D Bentley2 and Julian Parkhill2

Author Affiliations

1 Nuffield Department of Clinical Laboratory Sciences, Oxford University, John Radcliffe Hospital, Headington, Oxford, OX3 9DU, UK

2 The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, CB10 1SA, UK

3 The School of Veterinary Medicine and Science, The University of Nottingham, Sutton Bonington Campus, Sutton Bonington, Leicestershire, LE12 5RD, UK

4 Institute for Animal Health, Compton Laboratory, Compton, Newbury, Berks, RG20 7NN, UK

5 Dept. of Veterinary Medicine, The University of Cambridge, Cambridge, CB3 0ES, UK

6 Institute for Cell and Molecular Biosciences, The Medical School, University of Newcastle upon Tyne, Framlington Place, Newcastle upon Tyne, NE2 4HH, UK

7 Department of Biological Sciences, University of Warwick, Coventry, CV4 7AL, UK

8 Centre for Preventative Medicine, Animal Health Trust, Newmarket, Suffolk, CB8 7UU, UK

9 Veterinary Laboratories Agency, Weybridge, UK

For all author emails, please log on.

BMC Genomics 2009, 10:54  doi:10.1186/1471-2164-10-54

Published: 28 January 2009

Additional files

Additional File 1:

Table Pseudogenes S1: and partial genes in the S. uberis 0140J genome. Table S1: Table containing a list of the predicted products, systematic IDs, and putative mutations associated with pseudogenes and partial genes in the S. uberis 0140J genome.

Format: PDF Size: 69KB Download file

This file can be viewed with: Adobe Acrobat Reader

Open Data

Additional File 2:

Unique CDSs compared to other sequenced streptococci. Table containing a list of the systematic IDs and predicted products for CDSs in the S. uberis 0140J genome that do not have reciprocal Fasta matches in S. pyogenes Manfredo, S. equi 4047, S. zooepidemicus H70, S. thermophilus CNRZ1066, S. suis P1/7, S. pneumoniae TIGR4, S. sanguinis SK36, S. mutans UA159, S. agalactiae NEM316, and S. gordonii str. Challis substr. CH1.

Format: PDF Size: 73KB Download file

This file can be viewed with: Adobe Acrobat Reader

Open Data