Syntenic analysis. Syntenic alignment using orthologous genes as anchors. In the example at top right, a orthologous pair of TASP1 genes is used as an anchor to determine that there is no syntenic mouse pseudogene corresponding to a human GAPDH pseudogene located in an intron of TASP1. In the example at bottom right, two orthologous pairs of CST genes are used as anchors to identify a syntenic pair of intergenic regions, in which we found a syntenic pair GAPDH pseudogenes. Solid and open bars indicate exons and introns, respectively.
Liu et al. BMC Genomics 2009 10:480 doi:10.1186/1471-2164-10-480