Table 1 |
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|
Parametric gene set enrichment analysis of GO classes and KEGG pathways |
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|
GO category |
p-value |
KEGG pathway |
p-value |
|
|
|||
|
0% vs. 0.5 or 1.0% |
0% vs. 0.5 or 1.0% |
||
|
Sterol transport |
2.83E-08 |
Oxidative phosphorylation |
6.63E-12 |
|
Pheromone-dependent signal transduction during conjugation with cellular fusion |
5.20E-06 |
Arginine and proline metabolism |
1.59E-09 |
|
Aerobic respiration |
0.0009 |
Glutathione metabolism |
1.26E-05 |
|
Glutamate biosynthetic process |
0.0015 |
Citrate cycle (TCA cycle) |
1.74E-05 |
|
Tricarboxylic acid cycle |
0.0025 |
MAPK signalling pathway |
2.87E-05 |
|
Exocytosis |
0.0065 |
||
|
|
|||
|
0% vs. 2.8% |
0% vs. 2.8% |
||
|
Sterol transport |
1.67E-07 |
Arginine and proline metabolism |
2.50E-13 |
|
Pheromone-dependent signal transduction during conjugation with cellular fusion |
8.38E-06 |
Citrate cycle (TCA cycle) |
4.65E-07 |
|
Glutamate biosynthetic process |
7.23E-05 |
MAPK signalling pathway |
0.0002 |
|
Tricarboxylic acid cycle |
0.0006 |
Porphyrin metabolism |
0.0009 |
|
Aerobic respiration |
0.0032 |
Sulphur metabolism |
0.0039 |
|
Exocytosis |
0.0056 |
||
|
|
|||
|
0% vs. 20.9% |
0% vs. 20.9% |
||
|
Response to stress |
1.54E-06 |
Glyoxylate and dicarboxylate metabolism |
2.77E-17 |
|
Sterol transport |
2.27E-05 |
Citrate cycle (TCA cycle) |
3.16E-12 |
|
Meiosis |
0.0008 |
Bile acid biosynthesis |
3.05E-08 |
|
NADH oxidation |
0.0025 |
Ascorbate and aldarate metabolism |
5.83E-07 |
|
Sporulation |
0.0063 |
Nucleotide sugars metabolism |
3.18E-05 |
|
Sphingolipid biosynthetic process |
0.0075 |
Propanoate metabolism |
7.84E-05 |
|
Fatty acid metabolism |
0.0002 |
||
|
Pentose phosphate pathway |
0.0004 |
||
|
|
|||
|
0.5% vs. 1.0% |
0.5% vs. 1.0% |
||
|
|
|||
|
0.5 or 1.0% vs. 2.8% |
0.5 or 1.0% vs. 2.8% |
||
|
Glyoxylate and dicarboxylate metabolism |
6.15E-20 |
||
|
Fatty acid metabolism |
0.0001 |
||
|
Porphyrin metabolism |
0.0002 |
||
|
|
|||
|
0.5 or 1.0% vs. 20.9% |
0.5 or 1.0% vs. 20.9% |
||
|
Sporulation (sensu Fungi) |
0.0015 |
||
|
Pheromone-dependent signal transduction during conjugation with cellular fusion |
0.0027 |
||
|
Meiosis |
0.0048 |
||
|
|
|||
|
2.8% vs. 20.9% |
2.8% vs. 20.9% |
||
|
Response to stress |
1.1E-12 |
Glyoxylate and dicarboxylate metabolism |
3.93E-06 |
|
Sporulation (sensu Fungi) |
0.0003 |
Phenylalanine metabolism |
0.0064 |
|
Protein folding |
0.0013 |
Amino sugars metabolism |
|
|
Pheromone-dependent signal transduction during conjugation with cellular fusion |
0.0017 |
||
|
SRP-dependent co-translational protein targeting to membrane, translocation |
0.0019 |
||
|
Hexose transport |
0.0032 |
||
|
Iron ion homeostasis |
0.0077 |
||
|
|
|||
|
Pair wise comparison of transcriptome data from cells grown in glucose-limited chemostats receiving 0, 0.5, 1.0, 2.8 or 20.9% oxygen (p-values < 0.01). For 0.5 and 1.0% oxygen, the data has been combined and the p-values are averaged p-values. |
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|
Rintala et al. BMC Genomics 2009 10:461 doi:10.1186/1471-2164-10-461 |
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