Scatterplots showing strong preservation of gene significance across the three independent datasets. The scatterplots include the network genes colored by their module assignment in dataset 1. t-test statistic value for dataset 1 (x-axis) was compared to the t statistic value for dataset 2 (y-axis A) and dataset 3 (y-axis B). Genes that are highly differentially expressed in dataset 1 also tend to be differentially expressed in datasets 2 and 3. Note that Blue genes tend to be over-expressed in ALS patients while yellow genes tend to be under-expressed.
Saris et al. BMC Genomics 2009 10:405 doi:10.1186/1471-2164-10-405