Table 2

Top genes upregulated in CD16- compared to CD16+ Mo

CD16- Mo AU


Gene Symbol

CD16+/CD16- Ratio

p-value

Mean

SD

GeneTitle


S100A12

0,1

0,000

32609

4915

S100 calcium binding protein A12 (calgranulin C)

CSPG2

0,2

0,000

44600

1191

chondroitin sulfate proteoglycan 2 (versican)

CD14

0,2

0,000

29424

2503

CD14 antigen

CD36

0,2

0,000

10283

2743

CD36 antigen (collagen type I receptor, thrombospondin receptor)

CD99

0,2

0,000

11219

925

CD99 antigen

DREV1

0,3

0,000

16902

2260

DORA reverse strand protein 1

CSF3R

0,3

0,000

15383

2884

colony stimulating factor 3 receptor (granulocyte)

FLJ22662

0,3

0,000

24777

3886

hypothetical protein FLJ22662

MS4A6A

0,3

0,000

17295

2171

membrane-spanning 4-domains, subfamily A, member 6A

ITGAM

0,3

0,000

10344

2182

integrin, alpha M (complement component receptor 3)

SELL

0,3

0,038

18878

6604

selectin L (lymphocyte adhesion molecule 1)

CRTAP

0,4

0,000

13026

934

cartilage associated protein

S100A9

0,4

0,000

91116

15677

S100 calcium binding protein A9 (calgranulin B)

GPX1

0,4

0,000

35555

1707

glutathione peroxidase 1

PLP2

0,4

0,000

10014

1672

proteolipid protein 2 (colonic epithelium-enriched)

S100A8

0,4

0,000

114633

17191

S100 calcium binding protein A8 (calgranulin A)

PPBP

0,4

0,025

10279

3787

pro-platelet basic protein (chemokine (C-X-C motif) ligand 7)

FPR1

0,4

0,000

23743

4367

formyl peptide receptor 1

EGFL5

0,4

0,000

10378

1126

EGF-like-domain, multiple 5

MNDA

0,4

0,000

26939

7235

myeloid cell nuclear differentiation antigen

KCTD12

0,4

0,000

21488

1640

potassium channel tetramerisation domain containing 12

DKFZp434L142

0,4

0,000

10904

1594

hypothetical protein DKFZp434L142

GRN

0,5

0,000

22341

2163

granulin

LYZ

0,5

0,038

86499

26260

lysozyme (renal amyloidosis)

APLP2

0,5

0,000

23441

2191

amyloid beta (A4) precursor-like protein 2

ALDH2

0,5

0,000

14898

1814

aldehyde dehydrogenase 2 family (mitochondrial)

HIF1A

0,5

0,000

14221

3447

hypoxia-inducible factor 1, alpha subunit

TALDO1

0,5

0,000

21276

2781

transaldolase 1

IRF2BP2

0,5

0,000

21329

4404

interferon regulatory factor 2 binding protein 2

EVI2A

0,5

0,000

10200

1342

ecotropic viral integration site 2A

AMICA

0,5

0,000

10160

945

adhesion molecule AMICA

DPYD

0,5

0,000

10049

1957

dihydropyrimidine dehydrogenase


Shown are differentially expressed genes (>2-fold higher in CD16- compared to CD16+ Mo) with the highest expression levels (>10,000 AU). AU, arbitrary units.

Ancuta et al. BMC Genomics 2009 10:403   doi:10.1186/1471-2164-10-403

Open Data