Resolution:
standard / ## Figure 2.
Estimated false detection rates associated with different thresholds for miRNA-mRNA
expression correlations. The x-axis is a series of thresholds for the Pearson correlation coefficient. The
requirement of P < 0.01 was applied for all thresholds at the same time. The y-axis has false detection
rates for the corresponding thresholds. The dotted lines indicate that the estimated
false detection rate is ~5.7% when the threshold is chosen as Pearson correlation
coefficient r < = -0.56 and P < 0.01. For selected thresholds, the numbers aside show the total number of miRNA-mRNA
pairs satisfying the corresponding threshold and the estimated false detection rate.
The requirement of P < 0.01 alone has estimated false detection rate as ~14% in this dataset.
Peng |