Table 7

ChIP-Seq simulations of depth of sequencing for three model organisms

Fold Enrichment of Simulated Sites

Genome Size (Mb)

10×


C. elegans

100

2,400,000

800,000

D. melanogaster

123

3,500,000

1,000,000

A. thaliana

157

6,800,000

1,500,000


Number of reads required in order to identify greater than 95% of 1,000 simulated binding sites distributed over the genomes of C. elegans, D. melanogaster and A. thaliana for average fold enrichments of 5× and 10×. See Methods for details of the simulation.

Lefrançois et al. BMC Genomics 2009 10:37   doi:10.1186/1471-2164-10-37

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