Research article
Measuring differential gene expression by short read sequencing: quantitative comparison to 2-channel gene expression microarrays
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* Corresponding author: Amy A Caudy acaudy@princeton.edu
- † Equal contributors
BMC Genomics 2009, 10:221 doi:10.1186/1471-2164-10-221
fisher's exact test for differential expression analysis
Ann Loraine (2009-05-28 14:14) UNC Charlotte
I'm curious about the authors' use of Fisher's exact test of contingency tables for the short-reads differential expression testing. It's an easy test to perform and it would be great if it's appropriate to use in this setting. But I think the contingency tables, if I understand the approach, will have vastly different numbers in the cells of the table. How does the test perform under these conditions? I would welcome some additional discussion of this issue.
Competing interests
No competing interests.
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