BMC Genomics

official impact factor 4.21

Open Access Research article

A network-based integrative approach to prioritize reliable hits from multiple genome-wide RNAi screens in Drosophila

Li Wang1, Zhidong Tu2* and Fengzhu Sun1,3*

Author Affiliations

1 Molecular and Computational Biology Program, University of Southern California, Los Angeles, CA 90089, USA

2 Rosetta Inpharmatics, a wholly owned subsidiary of Merck & Co., Inc, 401 Terry Ave N, Seattle WA 98109, USA

3 MOE Key Laboratory of Bioinformatics and Bioinformatics Division, TNLIST/Department of Automation, Tsinghua University, Beijing, PR China

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BMC Genomics 2009, 10:220 doi:10.1186/1471-2164-10-220

Published: 12 May 2009

Additional files

Additional file 1:

Supplementary materials. This file contains all the supplementary text, tables and figures.

Format: PDF Size: 729KB Download file

This file can be viewed with: Adobe Acrobat Reader

Open Data

Additional file 2:

NePhe scores. This file contains the NePhe score results for both hits and nonhits of the 24 whole-genome RNAi screens.

Format: XLS Size: 7.7MB Download file

This file can be viewed with: Microsoft Excel Viewer

Open Data

Additional file 3:

R package NePhe. This file contains the source codes of the R package for computing NePhe scores.

Format: RAR Size: 8KB Download file

Open Data