Research article
Genome evolution driven by host adaptations results in a more virulent and antimicrobial-resistant Streptococcus pneumoniae serotype 14
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* Corresponding author: Cheng-Hsun Chiu chchiu@adm.cgmh.org.tw
- † Equal contributors
1 The CAS Key Laboratory of Genome Sciences and Information, Beijing Institute of Genomics, Chinese Academy of Sciences, 100029 Beijing, PR China
2 Graduate School of the Chinese Academy of Sciences, Chinese Academy of Sciences, 100029 Beijing, PR China
3 Department of Parasitology, Chang Gung University College of Medicine, Kweishan 333, Taoyuan, Taiwan
4 Department of Pediatrics, Chang Gung Children's Hospital, Chang Gung University College of Medicine, Kweishan 333, Taoyuan, Taiwan
BMC Genomics 2009, 10:158 doi:10.1186/1471-2164-10-158
Published: 13 April 2009Additional files
Additional file 1:
IS elements of the CGSP14 genome. The data show the list of the IS elements in the CGSP14 genome.
Format: DOC Size: 37KB Download file
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Additional file 2:
Orthologues shared among the seventeen S. pneumoniae genomes. The data represent the core genes of the seventeen S. pneumoniae genomes, assigned by their accession numbers in CGSP14
Format: TXT Size: 108KB Download file
Additional file 3:
COG assignment of the orthologous genes. The data show the alignment results by searching the core genes against COG database.
Format: TXT Size: 92KB Download file
Additional file 4:
Comparison of antimicrobial resistance determinants among the seventeen S. pneumoniae genomes. The data show antimicrobial resistance determinants in the seventeen S. pneumoniae genomes.
Format: XLS Size: 29KB Download file
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Additional file 5:
Capsule biosynthesis genes of CGSP14 and comparison of the capsular loci among three serotype 14 strains. This figure shows capsule biosynthesis genes of S. pneumoniae serotype 14 strains. Genes are represented by boxes colored according to the gene key, with gene designations above or below each box. Red bands indicate regions that are highly homologous between gene clusters.
Format: TIFF Size: 340KB Download file
Additional file 6:
Capsular biosynthesis pathway of S. pneumoniae CGSP14. This figure shows the capsule biosynthesis pathway of S. pneumoniae CGSP14.
Format: TIFF Size: 1.2MB Download file
Additional file 7:
Putative surface proteins based on computer prediction. The data show the list of putative surface proteins of S. pneumoniae CGSP14.
Format: DOC Size: 55KB Download file
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