Research article
Uncovering new signaling proteins and potential drug targets through the interactome analysis of Mycobacterium tuberculosis
1 National Key Laboratory of Agricultural Microbiology, Center for Proteomics Research, College of Life Science and Technology, Huazhong Agricultural University, Wuhan 430070, PR China
2 Department of Medicine, Lishui University, Lishui 323000, PR China
BMC Genomics 2009, 10:118 doi:10.1186/1471-2164-10-118
Published: 19 March 2009Additional files
Additional file 1:
A protein-protein interaction network of M. tuberculosis H37Rv. The data provided represent the protein interaction network of M. tuberculosis H37Rv generated from HPM method which composed with 793 individual proteins and 6091 interaction pairs.
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Additional file 2:
Top 20 highly connected Nodes in the network. The data provided represent the top 20 highly connected Nodes in the network.
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Additional file 3:
Hypothetical proteins in the network. The data present the hypothetical proteins in the network.
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Additional file 4:
Top 10 hits compounds in structure based virtual screen. The data provided top 10 hits compounds in structure based virtual screen.
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Additional file 5:
The interactome of Mycobacterium tuberculosis obtained based on the experimentally verified interactions from DIP. The data present all protein-protein interactions of Mycobacterium tuberculosis obtained based on the experimentally verified interactions from DIP.
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Additional file 6:
Identity, coverage and E-value of each query protein of Mycobacterium tuberculosis to the hit protein in DIP. The data described the identity, coverage and E-value of each query protein of Mycobacterium tuberculosis to the hit protein in DIP.
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Additional file 7:
Primers and plasmids used in the study. The data present the primers and plasmids used in the study.
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