NMD efficiency in 13 tissues of mice heterozygous for a truncating mutation in the Men1 gene. NMD efficiency is expressed as a ratio of the amount of mutant Men1 transcripts versus wild-type species, as measured by quantitative RT-PCR. Each bar on the graph represents the mean value of at least 3 independent measurements (± standard deviation) in four samples of the same tissue (two samples only were used for testis and ovary).
Zetoune et al. BMC Genetics 2008 9:83 doi:10.1186/1471-2156-9-83