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Open Access Highly Accessed Research article

Heterozygosity increases microsatellite mutation rate, linking it to demographic history

William Amos1*, Jonathan Flint2 and Xin Xu3

Author Affiliations

1 Department of Zoology, Downing Street, Cambridge, CB4 3DB, UK

2 Wellcome Trust Centre for Human Genetics, Roosevelt Drive, Oxford, OX3 7BN, UK

3 Program for Population Genetics, Harvard School of Public Health, 665 Huntington Ave, Boston, MA 02115, USA

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BMC Genetics 2008, 9:72  doi:10.1186/1471-2156-9-72

Published: 14 November 2008

Additional files

Additional file 1:

Coefficients for the predictor variables retained after backward simplification of general linear models (GLMs) fitted individually to data from 783 human microsatellite loci.

Format: DOC Size: 803KB Download file

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Open Data

Additional file 2:

Coefficients for the predictor variables retained after backward simplification of general linear models (GLMs) fitted individually to data from 783 human microsatellite loci (with phylogenetic correction using CAIC).

Format: DOC Size: 815KB Download file

This file can be viewed with: Microsoft Word Viewer

Open Data

Additional file 3:

Estimates of modern population size used in the current study

Format: DOC Size: 49KB Download file

This file can be viewed with: Microsoft Word Viewer

Open Data