Table 4

Summary of results in Table 3
MODEL
 Include Z
 Residualize by Z
 Ignore Z
MODEL 1: ADDITIVE
 +/-
 +/+
 +/+
MODEL 2: ADDITIVE WITH CONFOUNDING
 +/-
 +/-
 - -/-
MODEL 3: ADDITIVE WITH EFFECT MEDIATION
 +/-
 - -/- -
 -/-
MODEL 4: INTERACTION WITH MAIN EFFECT
 +/+
 +/+
 +/+
MODEL 5: INTERACTION WITH NO MAIN EFFECT
 +/+
 - -/- -
 - -/- -
MODEL 6: CONDITIONAL ASSOCIATION
 +/+
 - -/- -
 - -/- -

Results are given in pairs corresponding to RF and MARS, respectively:

"+" denotes reasonable TDR (> 80%) to detect genotype;

"-" denotes lower TDR (50% – 80%) to detect genotype;

and "--" denotes very low TDR (< 50%) to detect genotype.

Nonyane and Foulkes BMC Genetics 2008 9:71   doi:10.1186/1471-2156-9-71