Figure 4.

7B2 levels and PCSK2 activity are increased in B62D-3 F2 mice overexpressing Scg5. A) 7B2 pituitary levels, B) Pcsk2 mRNA expression, C) PCSK2 activity, D) pituitary α-MSH and E) pituitary ACTH levels in the three B62D-3 F2 genotypes (b6/b6, b6/cast and cast/cast).