Table 4

Comparison of MC1R nucleotide diversity and Tajima's D statistic to other sets of genes. These data include subjects from different ethnic groups calculated as a whole. The number of genes evaluated is shown in parentheses.


π × 10-4
θ × 10-4
# NS/kbp
#S/kbp
Tajima's D statistic

MC1R
10.1
64.2
38.9
18.9
-2.08
Telomere biology genesa (n = 7)
3.0
5.5
0.59
1.01
-1.365
Nuclear hormone receptor genesb (n = 40)
4.1
7.5
1.55
1.97
ND
Antigen processing and presenting genesb (n = 72)
4.7
8.3
2.29
1.99
ND
Reference genesb (n = 4950)
4.8
7.9
1.88
1.86
ND
Pharmaceutical Response genesc (n = 1598)
5.6
ND
ND
ND
negative
Environmental response genesd (n = 213)
6.7
ND
ND
ND
ND

aSavage et al. [2005].

bPungliya et al. [2004].

cSchneider et al. [2003].

dLivingston et al. [2004].

Abbreviations: NS, nonsynonymous, S, synonymous, ND, not determined in the reference manuscript.

Savage et al. BMC Genetics 2008 9:31   doi:10.1186/1471-2156-9-31