Table 5

Correlation coefficients of hypertension-associated polymorphism MAFs with latitude.

Polymorphism

Population

Adjusted Spearman Rank Correlation Score

Adjusted r2


CYP3A5 g.6980G>A

CEPH-HGDP

-0.621**

0.319

CEPH-HGDP + HapMap

-0.620**

0.349

CEPH-HGDP + HapMap + AIP

-0.603**

0.302


AGT g.802C>T

CEPH-HGDP

-0.718**

0.409

CEPH-HGDP + Others

-0.693**

0.373

CEPH-HGDP + Others + AIP

-0.518**

0.248


GNB3 g.825C>T

Others

-0.620**

0.278

Others + AIP

-0.300*

0.101


* significant at 0.05, ** significant at 0.01

CEPH-HGDP = Centre d'Etude du Polymorphisme Humain-Human Genome Diversity Panel.

AIP = Asian Indian population.

Others = data from other populations that were not part of CEPH-HGDP or HapMap.

For sample sizes, please see Additional file 1, Tables S4, S5, S6, for CYP3A5 g.6980G>A, AGT g.802C>T, and GNB3 g.825C>T, respectively.

Pemberton et al. BMC Genetics 2008 9:13   doi:10.1186/1471-2156-9-13

Open Data