Figure 1.

The effects of TE insertions. a) (i) TE inserts into an intron of a gene. (ii-v) show the possible effects of this integration; (ii) alternatively exon is created, (iii) TE contributes alternative 5'splice site, (iv) TE contributes alternative 3'splice site, (v) TE creates a constitutively spliced exon. b) (i) TE inserts into the first or last exon of a gene. (ii – iv) show the possible effect of this integration: (ii, iii) enlargement of first or last exon, (iv) TE activates an alternative intron.