|
Significant associations detected for the dilution-related traits and the Grey-Intensity trait. For each significant association, the position, and gene effect estimates (additive and dominance) are detailed. See Methods for further details about the trait categories. |
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| Chrom. |
Trait |
Position (cM) |
F-value |
pc-value |
Additive Effect |
Dominance Effect |
|
|
||||||
| 5 |
Quantitative-Dilution▲ |
68 |
452.0 |
<0.0001 |
0.93 *** |
-0.06 |
| 5 |
Quantitative-Black |
68 |
436.6 |
<0.0001 |
0.94 *** |
-0.11 * |
| 5 |
Quantitative-Red |
69 |
125.1 |
<0.0001 |
0.86 *** |
-0.14 |
| 28 |
Quantitative-Dilution▲ |
0 |
4.9 |
0.016 |
-0.19 ** |
0.00 |
| 28 |
Quantitative-Red |
0 |
5.9 |
0.019 |
-0.39 *** |
0.18 |
| 28 |
Grey-Intensity▲▲ |
1 |
5.3 |
0.016 |
-0.12 |
-0.32 ** |
|
Quantitative-Dilution (443 individuals included in analysis): White (1), Pale colour (2; Light-Red and Grey), Dark colour (3; Dark-Red and Black). Quantitative-Black (327): White, only whites of ED- genotype at MC1R (1), Grey (2), Black (3). Quantitative-Red (130): White, excluding whites of ED- genotype at MC1R (1), Light-Red (2), Dark-Red (3). Grey-Intensity (141): Light-Grey (1), Dark-Grey (2) pc-value: chromosome-wide p-value * p-value < 0.05; ** p-value < 0.01; ** p-value < 0.001 ▲ Includes MC1R genotype (ED-, E+e, ee) as a fixed effect. ▲▲ Includes SILV c.64A>G genotype as a fixed effect. | ||||||
Gutiérrez-Gil et al. BMC Genetics 2007 8:56 doi:10.1186/1471-2156-8-56 |
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