BMC Genetics

official impact factor 2.49

Open Access Methodology article

Analysis of case-parent trios at a locus with a deletion allele: association of GSTM1 with autism

Steven Buyske1*, Tanishia A Williams2, Audrey E Mars3,4, Edward S Stenroos2, Sue X Ming4,5,6, Rong Wang2, Madhura Sreenath2, Marivic F Factura3, Chitra Reddy5, George H Lambert3,4 and William G Johnson2,4

Author Affiliations

1 Departments of Statistics and Genetics, 110 Frelinghuysen Rd, Rutgers University, Piscataway, NJ 08854, USA

2 Department of Neurology, UMDNJ-Robert Wood Johnson Medical School, 675 Hoes Lane, Piscataway, NJ 08854, USA

3 Department of Pediatrics, UMDNJ-Robert Wood Johnson Medical School, 675 Hoes Lane, Piscataway, NJ 08854, USA

4 Center for Childhood Neurotoxicology & Exposure Assessment, UMDNJ-Robert Wood Johnson Medical School, 675 Hoes Lane, Piscataway, NJ 08854, USA

5 Department of Pediatrics, UMDNJ New Jersey Medical School, 90 Bergen Street, Newark, NJ 07103, USA

6 Department of Neuroscience, UMDNJ New Jersey Medical School, 90 Bergen Street, Newark, NJ 07103, USA

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BMC Genetics 2006, 7:8 doi:10.1186/1471-2156-7-8

Published: 10 February 2006

Additional files

Additional File 1:

This text file contains the complete R code needed for performing the test described in this paper, as well as a utility function for counting the case-parent types.

Format: R Size: 7KB Download file

Open Data