Table 1 |
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|
Summary of Dlk1-Gtl2 expression and imprinting in Gtl2lacZ and Gtl2Δ5'Neo mice. |
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|
Dlk1 |
Gtl2 |
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|
|
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|
Expression |
Imprinting |
Expression |
Imprinting |
|
|
|
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|
Gtl2lacZPat129 |
52% |
No change |
127% |
Biallelic |
|
Gtl2lacZPatB6 |
No change |
No change |
No change |
No change |
|
Gtl2lacZMat129 |
131% |
Biallelic |
50% |
No change |
|
Gtl2lacZMatB6 |
127% |
Biallelic |
60% |
No change |
|
Dlk1 |
Gtl2 |
|||
|
|
||||
|
Expression |
Imprinting |
Expression |
Imprinting |
|
|
|
||||
|
Gtl2Δ5'NeoPat129 |
60% |
No change |
132% |
Biallelic |
|
Gtl2Δ5'NeoPatB6 |
35% |
No change |
160% |
Biallelic |
|
Gtl2Δ5'NeoMat129 |
108% |
Biallelic |
83% |
No change |
|
Gtl2Δ5'NeoMatB6 |
127% |
Biallelic |
55% |
No change |
|
|
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|
The column "Expression" gives percent change in mRNA levels relative to wild type littermates; "No change" indicates that there is no deviation in expression from wild type. The column "Imprinting" indicates that imprinting is maintained ("No change") or that the silent allele of a given gene is activated ("biallelic"). |
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|
Steshina et al. BMC Genetics 2006 7:44 doi:10.1186/1471-2156-7-44 |
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