Table 5

Allele frequencies of the selected CYP7A1 htSNPs and mutation markers A. in the Mexican-American population.

#

SNP ID

Variation Allele 1/2

Observed genotype frequencies

Observed allele frequencies

Hardy-Wenberg


Homo Allele 1

Hetero

Homo Allele 2

Allele 1

Allele 2

Expect heterozygous

P value


1

rs10504255

A/G

0.71

0.25

0.03

0.84

0.16

0.27

0.79

2

rs8192879

C/T

0.41

0.42

0.18

0.61

0.39

0.47

0.34

3

rs11786580

C/T

0.75

0.25

0

0.87

0.13

0.22

0.45

4

rs8192874

T/C

1.00

0

0

1.00

0

5

rs2162459

A/G

0.59

0.31

0.10

0.75

0.25

0.38

0.13

6

rs3808607

T/G

0.62

0.30

0.09

0.76

0.24

0.37

0.09

7

rs7833904

T/A

0.64

0.30

0.07

0.79

0.21

0.33

0.37

8

rs1125226

A/C

0.62

0.30

0.08

0.78

0.22

0.34

0.18

9

rs1023652

C/G

0.67

0.26

0.07

0.81

0.19

0.32

0.14

10

1302 delTT

TT/–

1.00

0

0

1.00

0


B. in the African-American population


1

rs10504255

A/G

0.81

0.18

0.01

0.84

0.10

0.18

1.00

2

rs8192879

C/T

0.56

0.36

0.08

0.61

0.26

0.38

0.82

3

rs11786580

C/T

0.60

0.36

0.04

0.87

0.22

0.34

0.90

4

rs8192874

T/C

1.00

0

0

1.00

0

5

rs2162459

A/G

0.25

0.34

0.41

0.75

0.58

0.49

0.01

6

rs3808607

T/G

0.23

0.36

0.40

0.76

0.58

0.49

0.03

7

rs7833904

T/A

0.20

0.50

0.30

0.79

0.55

0.50

1.00

8

rs1125226

A/C

0.20

0.49

0.31

0.78

0.56

0.49

1.00

9

rs1023652

C/G

0.33

0.38

0.29

0.81

0.49

0.50

0.04

10

1302 delTT

TT/--

1.00

0

0

1.00

0


* Shadows indicate SNP nucleotides in P1 probe and target sequences.

Nakamoto et al. BMC Genetics 2006 7:29   doi:10.1186/1471-2156-7-29

Open Data