Table 3

Age at diagnosis in retinoblastoma patients according to phenotype and type of mutation. Statistical analysis using the Welch's unpaired t test.

Phenotype

Frameshift

Nonsense

Missense

Splicing

SP vs. NS-MS-FS


Unilateral

21.1

26.0

23.7

26.7

P = 0.7237

Bilateral

9.5

11.8

9.4

19.3

P = 0.0025

All

12.4

15.6

16.0

21.8

P = 0.0044

Unilateral vs. Bilateral

P = 0.0073

P = 0.0147

P = 0.3321


Valverde et al. BMC Genetics 2005 6:53   doi:10.1186/1471-2156-6-53

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