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Stability of methylation and expression of TIMP1 in subclones of four 5-azacytidine induced HPRT reactivants |
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| Subclones |
t11-az-4 (-/M) |
t11-az-8 (+/M)a |
t11-az-9 (+/M)a |
t11-az-10 (+/M) |
|
|
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| TIMP-, methylated (-/M) |
10 |
10 |
15 |
3 |
| TIMP+, Methylated (+/M) |
0 |
2a |
2a |
13 |
| TIMP+, Unmethylated (+/U) |
0 |
0 |
0 |
1 |
|
aExpression in these branches was initially weak and became silent after time in culture. ELK1 expression was initially retained in one of the t11-az-9 TIMP1+ clones but was not analyzed after TIMP1 expression was lost. The expression of ZNF41/157 was not examined in these subclones. | ||||
Anderson and Brown BMC Genetics 2005 6:48 doi:10.1186/1471-2156-6-48 |
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