Table 2

Distribution of Cftr genotypes in male offspring from breeding Cftr heterozygotes on the B6 and mixed backgrounds.

B6 Background

Mixed Background


Cftr

Observed

Expected

Observed

Expected


+/+

240

201

57

52

+/-

431

403

115

104

-/-

134

201

36

52

P

<0.00001 (0.01612)*

0.03749


Statistical analysis was by Chi-square. (*) P-value if the sample size for the B6 mice is adjusted to be equal to that of the mixed background mice, assuming the same distribution of genotypes.

Norkina and De Lisle BMC Genetics 2005 6:29   doi:10.1186/1471-2156-6-29

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