Table 2

Birth size by mothers or fathers H19 2992 genotype (ALSPAC cohort)

Mothers genotype
CC
CT
TT
PA
PD

(n = 550)
(n = 242)
(n = 30)



Weight (gm)
3457 ± 474
3543 ± 508
3595 ± 485
0.003
0.003
Length (cm)
50.7 ± 2.0
51.0 ± 1.9
51.1 ± 1.8
0.04
0.04
Head circ. (cm)
34.8 ± 1.2
35.1 ± 1.3
34.9 ± 1.4
0.07
0.03

(n = 164)
(n = 61)
(n = 9)


Cord IGF-II (ng/dl)
266 ± 72
312 ± 99
312 ± 92
0.0003
0.0001






Fathers genotype
CC
CT
TT
PA
PD

(n = 442)
(n = 201)
(n = 18)


Weight (gm)
3492 ± 491
3474 ± 472
3537 ± 519
0.9
0.7
Length (cm)
50.8 ± 1.9
50.8 ± 1.9
51.1 ± 1.7
0.8
0.9
Head circ. (cm)
34.9 ± 1.2
34.9 ± 1.2
35.0 ± 1.2
0.9
0.7

(n = 76)
(n = 37)
(n = 3)


Cord IGF-II (ng/dl)
270 ± 75
290 ± 93
245 ± 96
0.5
1.0

Mean ± SD, adjusted for sex, gestation and parity.

PA = P value for additive genetic model (per T allele)

PD = P value for dominant genetic model (CC versus T/*)

Petry et al. BMC Genetics 2005 6:22   doi:10.1186/1471-2156-6-22