Table 1

Birth size and cord IGF-II levels by offspring H19 2992 genotype (ALSPAC cohort)


CC
CT
TT
PA
PD

(n = 1075)
(n = 518)
(n = 54)



Weight (gm)
3468 ± 488
3522 ± 486
3524 ± 587
0.03
0.02
Length (cm)
50.7 ± 2.0
50.9 ± 2.0
50.9 ± 2.1
0.08
0.06
Head circ. (cm)
34.9 ± 1.2
34.9 ± 1.3
35.0 ± 1.6
0.3
0.4

(n = 226)
(n = 110)
(n = 13)


Cord IGF-II (ng/dl)
275 ± 78
277 ± 79
337 ± 91
0.1
0.3

Mean ± SD, adjusted for sex, gestation and parity.

PA = P value for additive genetic model (per T allele)

PD = P value for dominant genetic model (CC versus T/*)

Petry et al. BMC Genetics 2005 6:22   doi:10.1186/1471-2156-6-22