Table 1 |
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|
Population surveys of D negative blood donors documented D negative and screened by RHD PCR-SSP |
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|
Samples (n) |
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|
|
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|
Documented phenotype |
screened |
PCR-SSP positive |
D positive* |
|
|
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|
Testing as single samples† |
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|
Ccddee |
433 |
34 |
0 |
|
ccddEe |
271 |
5 |
2 |
|
CCddee |
24 |
4 |
0 |
|
CcddEe |
19 |
4 |
2 |
|
ccddEE |
6 |
1 |
0 |
|
CcddEE |
1 |
0 |
0 |
|
ccddee |
314 |
0 |
0 |
|
Testing as pools of 20 samples‡ |
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|
ccddee |
7,374 |
2 |
1 |
|
Total |
50 |
5 |
|
|
|
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|
*Samples uncovered on further analysis as weak D, partial D or D+/- chimera. † Positive for at least one of four RHD specific polymorphism tested (promoter, intron 4, exon 7 and 3' UTR). ‡Positive for at least one of three RHD specific polymorphism tested (promoter, intron 4, and 3' UTR). |
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Wagner et al. BMC Genetics 2001 2:10 doi:10.1186/1471-2156-2-10 |
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