Open Access Highly Accessed Research article

On the relationship between an Asian haplotype on chromosome 6 that reduces androstenone levels in boars and the differential expression of SULT2A1 in the testis

André M Hidalgo12*, John WM Bastiaansen1, Barbara Harlizius3, Hendrik-Jan Megens1, Ole Madsen1, Richard PMA Crooijmans1 and Martien AM Groenen1

Author Affiliations

1 Animal Breeding and Genomics Centre, Wageningen University, Wageningen, the Netherlands

2 Department of Animal Breeding and Genetics, Swedish University of Agricultural Sciences, Uppsala, Sweden

3 TOPIGS Research Center IPG, Beuningen, the Netherlands

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BMC Genetics 2014, 15:4  doi:10.1186/1471-2156-15-4

Published: 9 January 2014

Additional files

Additional file 1:

Position of the 46 SNPs in the QTL region on SSC6 of Sscrofa10.2.

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Additional file 2:

Haplotype effects and total number of animals per pig population.

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Additional file 3:

Haplotype effects estimated using only populations that had the third haplotype that was being compared to haplotypes 1 and 2.

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Additional file 4:

Average heterozygosity for the narrowed region. Average heterozygosity in 10,000 bp bins along the narrowed region for a heterozygous animal (A) and a homozygous animal (B).

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Additional file 5:

List of genes and the status of the exonic variation.

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Additional file 6:

The QTL effects for the C and T allele of the high- and low-androstenone haplotypes.

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Additional file 7:

Panels with control allele-specific expression. Log-transformed (base 2) data relation between observed and expected ratios of mixed genomic DNA from two homozygous animals for different alleles in three concentrations: 2.5 ng, 10 ng, and 40 ng.

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Additional file 8:

Genetic and physical map of the narrowed region (SSC6: 48,317,509 bp – 50,259,057 bp), showing its low-recombining nature.

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