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Open Access Research article

Insights into the European rabbit (Oryctolagus cuniculus) innate immune system: genetic diversity of the toll-like receptor 3 (TLR3) in wild populations and domestic breeds

Joana Abrantes13, Helena Areal12 and Pedro J Esteves14*

Author Affiliations

1 CIBIO/UP, Centro de Investigacao em Biodiversidade e Recursos Geneticos/Universidade do Porto, InBio, Laboratorio Associado, Campus Agrario de Vairao, Rua Padre Armando Quintas, number. 7, Vairao 4485-661, Portugal

2 Departamento de Zoologia e Antropologia da Faculdade de Ciencias da Universidade do Porto, Porto, Portugal

3 INSERM, U892, Universite de Nantes, Nantes 44007, France

4 CESPU, Instituto de Investigação e Formação Avançada em Ciências e Tecnologias da Saúde, Gandra, Portugal

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BMC Genetics 2013, 14:73  doi:10.1186/1471-2156-14-73

Published: 21 August 2013

Additional files

Additional file 1: Table S1:

List of the SNPs found for each population/breed and their location in the TLR3 gene (positions are according to the CDS of ENSOCUT00000017763 from Ensembl).

Format: DOC Size: 195KB Download file

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Open Data

Additional file 2: Table S2:

List of the TLR3 haplotypes found with indication of their frequency and occurrence in the populations/breeds analysed.

Format: DOCX Size: 75KB Download file

Open Data

Additional file 3: Table S3:

Amplification conditions of TLR3. Characterisation of the conditions used for TLR3 amplification. Positions are according to the rabbit TLR3 sequence (ENSOCUG00000017763).

Format: DOCX Size: 15KB Download file

Open Data