Table 5

SNPs associated with productive lifea
SNP Gene Least-squares means (SEM) Linear Dominance
0 1 2 Effect P value Q value P value Q value
rs109967779 ACAT2 2.05 (0.65) 1.24 (0.41) −0.18 (0.42) −1.18 0.0006 0.0014 0.5495 0.9408
rs133700190 AP3B1 3.74 (1.11) 1.16 (0.47) 0.15 (0.36) −1.42 0.0006 0.0014 0.2684 0.9053
rs110541595 ARL6IP1 0.22 (0.63) 1.49 (0.41) −0.12 (0.45) −0.45 0.2040 0.1193 0.0051 0.4845
rs110127056 ASL 1.49 (0.55) 0.90 (0.40) −0.11 (0.47) −0.82 0.0159 0.0204 0.6685 0.9798
rs43114141 AVP 0.23 (0.56) 1.24 (0.45) 0.15 (0.47) −0.12 0.7144 0.2797 0.0446 0.8474
rs109447102 CCDC86 −0.42 (1.21) −0.16 (0.49) 1.17 (0.35) 1.18 0.0074 0.0112 0.6685 0.9798
rs41711496 CD40 −0.50 (0.50) 0.71 (0.40) 2.28 (0.50) 1.39 <0.0001 0.0004 0.4864 0.9408
rs41857027 CFDP2 −0.69 (0.90) 0.87 (0.64) 1.27 (0.36) 0.81 0.0482 0.0489 0.4461 0.9408
rs109301586 COQ9 −0.67 (0.50) 0.71 (0.44) 2.34 (0.48) 1.50 <0.0001 0.0004 0.8009 0.9798
rs109443582 CSPP1 3.16 (3.99) −1.02 (0.72) 1.08 (0.34) 1.74 0.0147 0.0204 0.0124 0.5059
rs110270752 DEPDC7 −3.30 (1.02) 0.48 (0.48) 1.09 (0.36) 1.41 0.0005 0.0014 0.0202 0.5059
rs109503725 DSC2 0.28 (0.51) 0.35 (0.40) 1.61 (0.50) 0.67 0.0445 0.0478 0.2216 0.9053
rs43745234 FSHR −1.14 (0.82) 0.36 (0.40) 1.34 (0.39) 1.13 0.0023 0.0045 0.6438 0.9708
rs41893756 FUT1 −0.86 (1.04) −0.96 (0.49) 1.60 (0.35) 1.88 <0.0001 0.0004 0.0546 0.8487
rs109516714 GPLD1 −0.34 (0.63) 0.55 (0.41) 1.17 (0.45) 0.73 0.0351 0.0403 0.7998 0.9798
rs109711583 HSD17B12 2.01 (0.57) 0.80 (0.39) −0.08 (0.47) −1.03 0.0030 0.0053 0.7318 0.9798
rs109769865 HSD17B6 0.25 (1.42) −0.80 (0.56) 1.16 (0.34) 1.35 0.0054 0.0090 0.0915 0.8487
rs110828053 HSD17B7 2.01 (1.18) 1.24 (0.47) 0.34 (0.35) −0.87 0.0397 0.0441 0.9303 0.9830
HSP70C895D HSPA1A 1.39 (0.84) 1.27 (0.43) 0.07 (0.38) −0.90 0.0155 0.0204 0.3526 0.9053
rs110789098 IBSP 0.65 (0.56) 1.36 (0.42) −0.25 (0.47) −0.58 0.0888 0.0664 0.0213 0.5059
rs111015912 LDB3 3.01 (1.10) 1.87 (0.44) −0.12 (0.36) −1.81 <0.0001 0.0004 0.5322 0.9408
rs41256848 LHCGR 1.97 (0.60) 0.71 (0.38) 0.03 (0.46) −0.94 0.0061 0.0097 0.5546 0.9408
rs134011564 MARVELD1 2.34 (3.77) 0.81 (0.36) −0.87 (0.71) −1.67 0.0188 0.0232 0.9690 0.9830
rs41859871 MON1B 5.54 (2.25) 1.72 (0.55) 0.31 (0.33) −1.65 0.0018 0.0040 0.3340 0.9053
rs109761676 MS4A8B −1.96 (0.96) 0.33 (0.43) 1.46 (0.39) 1.43 0.0004 0.0014 0.3471 0.9053
rs133762601 NEU3 −0.81 (0.66) −1.29 (1.02) 0.98 (0.34) 0.99 0.0030 0.0053 0.1963 0.9053
rs134264563 OCLN 1.84 (0.88) 1.03 (0.41) 0.01 (0.38) −0.96 0.0113 0.0164 0.8560 0.9798
rs111027720 PARM1 3.06 (0.54) 0.77 (0.39) −1.03 (0.46) −2.03 <0.0001 0.0004 0.6161 0.9708
rs109813896 PCCB 2.00 (0.68) 1.05 (0.41) 0.07 (0.41) −1.06 0.0023 0.0045 0.9700 0.9830
rs109629628 PMM2 3.26 (0.66) 0.94 (0.39) −0.48 (0.43) −1.76 <0.0001 0.0004 0.3833 0.9408
rs133729105 RABEP2 −0.86 (0.62) 0.25 (0.40) 1.68 (0.42) 1.30 <0.0001 0.0004 0.7495 0.9798
rs42158454 SYTL2 N/A N/A 1.88 (0.63) 0.42 (0.33) −1.46 0.0261 0.0311 N/A N/A
rs110660625 TBC1D24 2.12 (0.70) 1.00 (0.41) −0.11 (0.39) −1.17 0.0006 0.0014 0.9830 0.9830
rs110805802 TDRKH −4.35 (1.72) −0.47 (0.55) 1.20 (0.33) 2.00 <0.0001 0.0004 0.2737 0.9053
rs134282928 WBP1 2.73 (3.26) −0.26 (0.53) 1.01 (0.35) 1.07 0.0484 0.0489 0.2112 0.9053
rs110883602 ZP2 −1.06 (0.64) 1.05 (0.48) 1.67 (0.47) 1.25 0.0005 0.0014 0.1876 0.9053

aSingle nucleotide polymorphism represented as the rs number given by the National Center for Biotechnology Information database SNP. For entries not beginning with rs, the abbreviation given by previous researchers was used.

Cochran et al.

Cochran et al. BMC Genetics 2013 14:49   doi:10.1186/1471-2156-14-49

Open Data