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Open Access Highly Accessed Research article

Discovery of single nucleotide polymorphisms in candidate genes associated with fertility and production traits in Holstein cattle

Sarah D Cochran1, John B Cole2, Daniel J Null2 and Peter J Hansen1*

Author Affiliations

1 Department of Animal Sciences, D.H. Barron Reproductive and Perinatal Biology Research Program, and Genetics Institute, University of Florida, Gainesville, FL 32611-0910, USA

2 Animal Improvement Programs Laboratory Agricultural Research Service, USDA, Beltsville, MD 20705-2350, USA

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BMC Genetics 2013, 14:49  doi:10.1186/1471-2156-14-49

Published: 7 June 2013

Additional files

Additional file 1: Table S1:

Predicted transmitting ability for selected traits of bulls used for genotyping. Table S2. Source of genes included in SNP array. Table S3. Full list of SNPs used in array.

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Additional file 2: Table S4:

Correlations among predicted transmitting ability for traits on bulls used for genotyping. Table S5. Correlations, within DPR class, among predicted transmitting ability for traits on bulls used for genotyping. Table S6. Information for all SNPs with minor allele frequencies (MAF) > 5% and call rates > 70%.

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Additional file 3: Table S7:

Genetic standard deviations of SNPs associated with daughter pregnancy rate. Table S8. Effect of tissue type in which genes were identified on the percent of genes that were significantly associated with daughter pregnancy rate (DPR). Figure S1. The ubiquitin pathway contains an overrepresentation of daughter pregnancy rate genes. Figure S2. Transcription factors which regulate daughter pregnancy rate genes.

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