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Open Access Research article

Genome-wide association study of antibody response to Newcastle disease virus in chicken

Chenglong Luo13, Hao Qu13, Jie Ma13, Jie Wang13, Chunyu Li13, Chunfen Yang13, Xiaoxiang Hu2, Ning Li2 and Dingming Shu13*

  • * Corresponding author: Dingming Shu

  • † Equal contributors

Author Affiliations

1 Institute of Animal Science, Guangdong Academy of Agricultural Sciences, 1 Dafeng 1st Street, Wushan, Tianhe District, Guangzhou, Guangdong, 510640, China

2 State Key Laboratory for Agro-Biotechnology, China Agricultural University, Beijing, 100193, China

3 State Key Laboratory of Livestock and Poultry Breeding, Guangzhou, 510640, China

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BMC Genetics 2013, 14:42  doi:10.1186/1471-2156-14-42

Published: 10 May 2013

Additional files

Additional file 1: Figure S1:

Distribution of the adjusted antibody response to the Newcastle disease virus in the F2 population. The data fitted the normal distribution (Shapiro-Wilk W test P=0.5527).

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Additional file 2: Table S1:

SNP markers used in the genome-wide association study.

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Additional file 3: Table S2:

SNPs associated with antibody response to Newcastle disease virus (P<1.00×10-4).

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Additional file 4: Figure S2:

Pattern of linkage disequilibrium on chicken (Gallus gallus) chromosome 1.

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Additional file 5: Table S3:

Functional annotation of candidate genes by KEGG and Interpro analysis in chickens (P<0.1).

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Additional file 6: Figure S3:

Network of gene correlation for genes in candidate regions related to antibody response to Newcastle disease virus (P<1.00×10-4). Yellow ellipses indicate genes. Green lines, red lines and blue lines indicate pathways based on GenMAPP, KEGG and BioCarta, respectively. The numbers indicate the number of pathways related to the two genes.

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