Table 1

Accuracy of imputation using tagSNP selected for different values of rt2 on chromosome 12
rt2 Number of tagSNP Number of SNP genomewide Average distance between SNP (Mb) Imputation accuracy ( IA )
0.1 33 1295 1.86 0.960
0.2 79 3100 0.79 0.970
0.3 158 6199 0.40 0.976
0.4 266 10436 0.24 0.980
0.5 399 15654 0.16 0.982

rt2 = Threshold of LD in statistical selection, Number of tagSNP = Number of SNP selected for a particular rt2, Number of SNP Genomewide = The equivalent number of SNP that are needed genome-wide to keep the same average inter-marker distance. Average distance between SNP (Mb) = Average distance between tagSNP selected, Imputation accuracy (IA) = Imputation accuracy of non-tagSNP. Results using simulated data.

Gualdrón Duarte et al.

Gualdrón Duarte et al. BMC Genetics 2013 14:38   doi:10.1186/1471-2156-14-38

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