Table 4

A summary of the tests for departures from neutrality for an 8063bp region of CYP3A5
Global populations Ethiopian populations
African-Americans Europeans Han Chinese Afar Amhara Anuak Maale Oromo
Sample size 23 24 23 75 76 76 76 76
Nucleotide diversity (π) 5.4 x 10-4 9 x 10-5 1.1 x 10-4 2.1 x 10-4 2.5 x 10-4 3.6 x 10-4 3.5 x 10-4 2.2 x 10-4
McDonald-Kreitman test 0.475 0.50 0.777 0.462 0.475 0.576 1.00 0.777
Tajima’s D −1.04 −1.92 −1.21 −1.46 −1.13 −1.26 −0.96 −1.79
Fu and Li’s D* −0.97 −2.86 −1.82 −1.19 0.12 −2.72 −0.11 −1.05
Fu and Li’s F* −1.17 −3.00 −1.91 −1.54 −0.43 −2.57 −0.53 −1.58
Fu and Li’s D −0.64 −1.37 −1.45 −1.56 −0.08 −1.93 0.73 −0.96
Fu and Li’s F −0.92 −1.81 −1.55 −1.79 −0.52 −1.96 0.13 −1.48
Fu’s FS −31.06 −5.71 −1.54 −9.48 −11.74 −18.44 −11.08 −22.84
Strobeck’s S 1.00 0.999 0.929 1.00 1.00 1.00 1.00 1.00
Fay and Wu’s H statistic −0.13140 −3.25532 −1.89372 0.10774 −0.23998 −0.47177 −0.87086 −1.75514

Statistically significant departures from neutrality, following Bonferonni correction (correction for 8 tests; adjusted p≤0.00625) are shown in bold.

Bains et al.

Bains et al. BMC Genetics 2013 14:34   doi:10.1186/1471-2156-14-34

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