Comparison of β-defensin-containing chromosomal regions among human, pig, and cattle genomes. The evolutionarily conserved flanking markers and the clustered β-defensin genes are shown. The genes with orthologous relationships are indicated by lines among maps of different species. The names of the β-defensin genes are indicated with only numbers without species-specific symbols (DEFB for human, BBD for cattle, and pBD for pigs). Pseudogenes or partial genes identified in the pig genome sequencing results at NCBI are shown as dotted lines. Information from genome build 37.2, Sscrofa10.2, and Btau5.2 were used for humans, pigs, and cattle, respectively. 1Some of the cattle β-defensin genes have less typical names, including TAP, LAP, and EBD.
Choi et al. BMC Genetics 2012 13:98 doi:10.1186/1471-2156-13-98