Figure 2.

Simulated genotype-specific differences in the dynamics of drug resistance as described by a model (2) in Appendix 1. The system simulation focuses on uninfected cell, x (A), infected cells, y, for wild-type virus (solid line) and mutant virus (dash lines) (B), and free virus, v, for wild-type virus (solid line) and mutant virus (dash line) (C), and relative frequency of mutant virus in free virus (solid line) and infected cell population (dash line) (D).

Hou et al. BMC Genetics 2012 13:91   doi:10.1186/1471-2156-13-91
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