Table 3

Comparison of the haplotype frequencies in the GSTA gene cluster of the populations from Tver, Murom, and Kursk with those from the HapMap Project (CEU, CHB, JPT, and YRI) *
MUROM KURSK СЕU CHB JPT YRI Number of haploblock The level of significance
TVER 0,6746 0,8353 0,8534 <0,0001 <0,0001 0,0269 I 0,004
0,9599 0,4282 0,6984 <0,0001 <0,0001 <0,0001 II 0,0025
0,9030 0,3306 0,0403 <0,0001 <0,0001 <0,0001 III 0,0025
0,8238 0,2076 0,0326 <0,0001 <0,0001 0,0065 IV 0,0019
0,0484 0,3957 0,2428 0,6452 V 0,0025
0,4538 0,9276 0,4634 VI 0,0025
MUROM 0,4641 0,4574 <0,0001 <0,0001 <0,0001 I 0,004
0,5661 0,5307 <0.0001 <0.0001 <0,0001 II 0,0025
0,1764 0,1188 <0.0001 <0.0001 <0,0001 III 0,0025
0,1599 0,0408 <0,0001 <0,0001 0,0006 IV 0,0019
0,5052 0,5524 0,0031 V 0,0025
0,2664 0,8195 VI 0,0025
KURSK 0,9266 <0,0001 <0,0001 0,0097 I 0,004
0,1321 <0.0001 <0.0001 <0,0001 II 0,0025
0,0013 <0.0001 <0.0001 <0.0001 III 0,0025
0,2053 <0,0001 <0,0001 0,0006 IV 0,0019
0,9682 0,1181 V 0,0025
0,2694 VI 0,0025

* Pairwise P-values are presented. The last column contains Bonferroni adjusted P-values calculated for each block. The calculations was performed using the formula P = 0.05/ ([n × a] – 1), where “n” is the number of haplotypes and “a” is the number of populations [16]. The absence of some haploblocks in the CHB, JPT, and YRI populations did not allow us to compare these populations; the respective columns are marked with dashes on the corresponding lines.

Filippova et al.

Filippova et al. BMC Genetics 2012 13:89   doi:10.1186/1471-2156-13-89

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