Table 3 |
||||||||
| Comparison of the haplotype frequencies in the GSTA gene cluster of the populations from Tver, Murom, and Kursk with those from the HapMap Project (CEU, CHB, JPT, and YRI) * | ||||||||
| MUROM | KURSK | СЕU | CHB | JPT | YRI | Number of haploblock | The level of significance | |
| TVER | 0,6746 | 0,8353 | 0,8534 | <0,0001 | <0,0001 | 0,0269 | I | 0,004 |
| 0,9599 | 0,4282 | 0,6984 | <0,0001 | <0,0001 | <0,0001 | II | 0,0025 | |
| 0,9030 | 0,3306 | 0,0403 | <0,0001 | <0,0001 | <0,0001 | III | 0,0025 | |
| 0,8238 | 0,2076 | 0,0326 | <0,0001 | <0,0001 | 0,0065 | IV | 0,0019 | |
| 0,0484 | 0,3957 | 0,2428 | ― | ― | 0,6452 | V | 0,0025 | |
| 0,4538 | 0,9276 | 0,4634 | ― | ― | ― | VI | 0,0025 | |
| MUROM | 0,4641 | 0,4574 | <0,0001 | <0,0001 | <0,0001 | I | 0,004 | |
| 0,5661 | 0,5307 | <0.0001 | <0.0001 | <0,0001 | II | 0,0025 | ||
| 0,1764 | 0,1188 | <0.0001 | <0.0001 | <0,0001 | III | 0,0025 | ||
| 0,1599 | 0,0408 | <0,0001 | <0,0001 | 0,0006 | IV | 0,0019 | ||
| 0,5052 | 0,5524 | ― | ― | 0,0031 | V | 0,0025 | ||
| 0,2664 | 0,8195 | ― | ― | ― | VI | 0,0025 | ||
| KURSK | 0,9266 | <0,0001 | <0,0001 | 0,0097 | I | 0,004 | ||
| 0,1321 | <0.0001 | <0.0001 | <0,0001 | II | 0,0025 | |||
| 0,0013 | <0.0001 | <0.0001 | <0.0001 | III | 0,0025 | |||
| 0,2053 | <0,0001 | <0,0001 | 0,0006 | IV | 0,0019 | |||
| 0,9682 | ― | ― | 0,1181 | V | 0,0025 | |||
| 0,2694 | ― | ― | ― | VI | 0,0025 | |||
* Pairwise P-values are presented. The last column contains Bonferroni adjusted P-values calculated for each block. The calculations was performed using the formula P = 0.05/ ([n × a] – 1), where “n” is the number of haplotypes and “a” is the number of populations [16]. The absence of some haploblocks in the CHB, JPT, and YRI populations did not allow us to compare these populations; the respective columns are marked with dashes on the corresponding lines.
Filippova et al. BMC Genetics 2012 13:89 doi:10.1186/1471-2156-13-89